2-(4-溴苯基)噻吩-3-胺合成路线 （共 4 条）
反应条件
hydrogenchloride in ethyl acetate T=0 - 20°C;
参考文献
Dominguez-Manzanares, Esteban
Patent: US2006/276532 A1, 2006 ;
Location in patent: Page/Page column 4 ;
反应条件
1: N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile / 1,2-dichloro-ethane / Inert atmosphere 2: triethylamine / Inert atmosphere 3: sulfuric acid / Inert atmosphere 4: sodium ethanolate / toluene / Inert atmosphere 5: sulfuric acid / Inert atmosphere View Scheme
参考文献
Mitchell, David; Coppert, David M.; Moynihan, Humphrey A.; Lorenz, Kurt T.; Kissane, Marie; McNamara, Orla A.; Maguire, Anita R.
Organic Process Research and Development, 2011 , vol. 15, # 5 p. 981 - 985
反应条件
1: triethylamine / Inert atmosphere 2: sulfuric acid / Inert atmosphere 3: sodium ethanolate / toluene / Inert atmosphere 4: sulfuric acid / Inert atmosphere View Scheme
参考文献
Mitchell, David; Coppert, David M.; Moynihan, Humphrey A.; Lorenz, Kurt T.; Kissane, Marie; McNamara, Orla A.; Maguire, Anita R.
Organic Process Research and Development, 2011 , vol. 15, # 5 p. 981 - 985
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane
T=0 - 20°C;
参考文献
Dominguez-Manzanares, Esteban
Patent: US2006/276532 A1, 2006 ;
Location in patent: Page/Page column 4-5 ;
