3-甲基-2(1H)-吡啶硫酮合成路线 （共 7 条）
反应条件
1: With thiourea in ethanol T=20°C; 5 h; Heating / reflux; 2: With sodium hydroxide in ethanol; water 1 h; Heating / reflux;
参考文献
ACTELION PHARMACEUTICALS LTD.
Patent: WO2004/33418 A2, 2004 ;
Location in patent: Page 35 ;
WO 2004/033418 A2
反应条件
diphosphorus pentasulfide; sodium chloride; potassium carbonate in chloroform; water
参考文献
Sankyo Company, Limited
Patent: US5541317 A1, 1996 ;
参考文献
Sankyo Company, Limited
Patent: US5541317 A1, 1996 ;
反应条件
pyridine; diphosphorus pentasulfide
参考文献
Zeneca Limited
Patent: US5821246 A1, 1998 ;
反应条件
1: 40 percent / diethylcarbamoyl chloride / acetonitrile / 6 h / Heating 2: 1.) anisole, mercury(II) acetate, 2.) aq. NaOH, NaBH4 / 1.) TFA, 0 deg C, 15 min, 2.) RT, 1.5 h View Scheme
参考文献
Sato, Nobuhiro; Nagano, Eiichi
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 3 p. 691 - 698
反应条件
1: NaNO2, aq. H2SO4 2: P2S5 / 160 °C View Scheme
参考文献
Hirai, Koichi; Iwano, Yuji; Mikoshiba, Isamu; Koyama, Hiroo; Nishi, Takahide
Heterocycles, 1994 , vol. 38, # 2 p. 277 - 280
反应条件
dihydrogen peroxide in acetic acid T=80°C;
参考文献
Lobana, Tarlok S.; Kinoshita, Isamu; Kimura, Kentaro; Nishioka, Takanori; Shiomi, Daisuke; Isobe, Kiyoshi
European Journal of Inorganic Chemistry, 2004 , # 2 p. 356 - 367
