1-氯-3-(2-羟基乙氧基)丙-2-醇合成路线 （共 10 条）
参考文献
Pallavicini, Marco; Valoti, Ermanno; Villa, Luigi
Enantiomer, 2001 , vol. 6, # 5 p. 267 - 273
反应条件
boron trifluoride diethyl etherate T=80°C;
参考文献
Maeda, Hirokazu; Kikui, Takashi; Nakatsuji, Yohji; Okahara, Mitsuo
Journal of Organic Chemistry, 1982 , vol. 47, # 26 p. 5167 - 5171
参考文献
Petrow; Stephenson
Journal of Pharmacy and Pharmacology, 1955 , vol. 7, p. 198,203
反应条件
potassium hydroxide im Ueberschuss bei niedriger Temperatur;
参考文献
Kharasch; Nudenberg
Journal of Organic Chemistry, 1943 , vol. 8, p. 189
反应条件
1: 53 percent / 26percent aq. NH3, K2CO3 / 55 h / Ambient temperature 2: 53 percent / tert-BuONa / dioxane; 2-methyl-propan-2-ol / 2.5 h / 40 °C View Scheme
参考文献
Maeda, Hirokazu; Kikui, Takashi; Nakatsuji, Yohji; Okahara, Mitsuo
Journal of Organic Chemistry, 1982 , vol. 47, # 26 p. 5167 - 5171
反应条件
ammonium hydroxide; potassium carbonate 55 h; Ambient temperature;
参考文献
Maeda, Hirokazu; Kikui, Takashi; Nakatsuji, Yohji; Okahara, Mitsuo
Journal of Organic Chemistry, 1982 , vol. 47, # 26 p. 5167 - 5171
反应条件
potassium hydroxide in ethanol
参考文献
Pallavicini, Marco; Valoti, Ermanno; Villa, Luigi
Enantiomer, 2001 , vol. 6, # 5 p. 267 - 273
反应条件
1: 53 percent / 26percent aq. NH3, K2CO3 / 55 h / Ambient temperature
2: 43 percent / tert-BuONa / dioxane; 2-methyl-propan-2-ol / 2.5 h / 40 °C
View Scheme
参考文献
Maeda, Hirokazu; Kikui, Takashi; Nakatsuji, Yohji; Okahara, Mitsuo
Journal of Organic Chemistry, 1982 , vol. 47, # 26 p. 5167 - 5171
反应条件
1: KOH / aq. ethanol
2: 95 percent / pyridine / 1 h / 90 °C
3: (R)-1-phenylethylamine / propan-2-ol
4: aq. NaOH / 1 h / 90 °C
View Scheme
参考文献
Pallavicini, Marco; Valoti, Ermanno; Villa, Luigi
Enantiomer, 2001 , vol. 6, # 5 p. 267 - 273
反应条件
1: KOH / aq. ethanol
2: 95 percent / pyridine / 1 h / 90 °C
3: (R)-1-phenylethylamine / propan-2-ol
4: aq. NaOH / 1 h / 90 °C
View Scheme
参考文献
Pallavicini, Marco; Valoti, Ermanno; Villa, Luigi
Enantiomer, 2001 , vol. 6, # 5 p. 267 - 273
