5-氨基-2-甲氧基吡啶-4-羧酸合成路线 (共 3 条)
反应条件
potassium hydroxide 18 h; Heating;
参考文献
Rewcastle, Gordon W.; Denny, William A.; Winters, R. Thomas; Colbry, Norman L.; Showalter, H. D. Hollis
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 18 p. 2221 - 2226
反应条件
1: 94 percent / dioxane / 0.5 h / Heating 2: 67 percent / TMEDA, BuLi / diethyl ether; hexane / 1.) -40 deg C, 16 h, 2.) -40 deg C to r.t., 1 h 3: 93 percent / aq. KOH / 18 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 18 p. 2221 - 2226
反应条件
1: 67 percent / TMEDA, BuLi / diethyl ether; hexane / 1.) -40 deg C, 16 h, 2.) -40 deg C to r.t., 1 h 2: 93 percent / aq. KOH / 18 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 18 p. 2221 - 2226