反应条件
2.1: 88 percent / DCC; DMSO; 85 percent H3PO4 / benzene / 135 h
3.1: 96 percent / NaBH4 / tetrahydrofuran / 1 h / -20 °C
4.1: 98 percent / N-chlorosiccinimide; Me2S / CH2Cl2 / 2.5 h / 0 °C
5.1: 65 percent / n-BuLi
6.1: 100 percent / LiBHEt3; Pd(dppp)Cl2 / tetrahydrofuran / 3 h / 0 °C
7.1: N-chlorosuccinimide; Me2S / CH2Cl2 / 2.5 h / 0 °C
8.1: 79 percent / n-BuLi
9.1: LiBHEt3; Pd(dppp)Cl2 / tetrahydrofuran
10.1: TBAF / tetrahydrofuran
11.1: Cp2ZrCl2 / 1,2-dichloro-ethane; hexane
11.2: 89 percent / NiCl2(PPh3)2; n-BuLi / tetrahydrofuran; hexane
View Scheme
参考文献
Lipshutz, Bruce H.; Bulow, Gerd; Fernandez-Lazaro, Fernando; Kim, Sung-Kyu; Lowe, Richard; Mollard, Paul; Stevens, Kirk L.
Journal of the American Chemical Society, 1999 , vol. 121, # 50 p. 11664 - 11673
