1: With sulfuric acid; sodium nitrite in tetrahydrofuran; water T=0°C; 1 h; 2: With copper; potassium iodide in tetrahydrofuran; water T=0 - 20°C; 1.5 h;
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; water
T=85°C; Suzuki coupling;
参考文献
Mewshaw, Richard E.; Bowen, S. Marc; Harris, Heather A.; Xu, Zhang B.; Manas, Eric S.; Cohn, Stephen T.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 4 p. 902 - 906