4-氧代-4H-苯并吡喃-2-羧酸甲酯合成路线 （共 10 条）
反应条件
DPAT in toluene T=80°C; 4 h;
参考文献
Sakamoto, Masami; Yoshiwara, Kazuya; Yagishita, Fumitoshi; Yoshida, Wataru; Mino, Takashi; Fujita, Tsutomu
Research on Chemical Intermediates, 2013 , vol. 39, # 1 p. 385 - 395
反应条件
sulfuric acid; sodium hydrogencarbonate in methanol
参考文献
Merrell Pharmaceuticals Inc.
Patent: US5668143 A1, 1997 ;
反应条件
sodium methylate in methanol; benzene 8 h; Heating;
参考文献
Reddy, K. R. S.; Srimannarayana, G.; Rao, N. V. Subba
Journal of the Indian Chemical Society, 1986 , vol. 63, p. 600 - 602
反应条件
1: in ethanol T=30 - 35°C; 0.5 h; 2: With acetic acid in ethanol 0.5 h; Reflux;
参考文献
Vydzhak; Panchishin, S. Ya.
Russian Journal of General Chemistry, 2008 , vol. 78, # 12 p. 2391 - 2397
反应条件
sodium methylate in methanol Knoevenagel Condensation; 3 h; RefluxInert atmosphere;
参考文献
Sapegin, Alexander V.; Kalinin, Stanislav A.; Smirnov, Alexey V.; Dorogov, Mikhail V.; Krasavin, Mikhail
Tetrahedron, 2014 , vol. 70, # 5 p. 1077 - 1083
反应条件
1: in ethanol T=30 - 35°C; 0.5 h; 2: With acetic acid in ethanol 0.5 h; Reflux;
参考文献
Vydzhak; Panchishin, S. Ya.
Russian Journal of General Chemistry, 2008 , vol. 78, # 12 p. 2391 - 2397
反应条件
1: in ethanol T=30 - 35°C; 0.5 h; 2: With acetic acid in ethanol 0.5 h; Reflux;
参考文献
Vydzhak; Panchishin, S. Ya.
Russian Journal of General Chemistry, 2008 , vol. 78, # 12 p. 2391 - 2397
反应条件
1: sodium hydride / Erhitzen des Reaktionsprodukts mit Essigsaeure und wss. Salzsaeure und anschliessend mit wss. Schwefelsaeure 2: sulfuric acid View Scheme
参考文献
Schmutz et al.
Helvetica Chimica Acta, 1951 , vol. 34, p. 767,774
反应条件
hydrogenchloride 2 h; Heating;
参考文献
Goerlitzer; Badia; Jones
Pharmazie, 2001 , vol. 56, # 5 p. 401 - 406
反应条件
Yield given. Multistep reaction;
参考文献
Tapia, I.; Alcazar, V.; Moran, J. R.
Canadian Journal of Chemistry, 1990 , vol. 68, # 12 p. 2190 - 2191
