阿尔法,阿尔法,阿尔法位-三氟-间-甲苯异硫氰合成路线 （共 16 条）
反应条件
1: With triethylamine in tetrahydrofuran; water T=0 - 20°C; 3.5 h; 2: With hydrogenchloride in tetrahydrofuran; water Reflux;
参考文献
US2011/105565 A1, ;
Page/Page column 26-28 ;
参考文献
Coppola, Gary M.; Damon, Robert E.; Eskesen, J. Bruce; France, Dennis S.; Paterniti Jr., James R.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 809 - 812
反应条件
2: HCl / H2O / 12 h / Heating View Scheme
参考文献
Cherbuliez,E. et al.
Helvetica Chimica Acta, 1966 , vol. 49, p. 2408 - 2415
反应条件
ammonium hydroxide in water; ethyl acetate T=20°C;
参考文献
Jamir, Latonglila; Sinha, Upasana Bora; Nath, Jayashree; Patel, Bhisma K.
Synthetic Communications, 2012 , vol. 42, # 7 p. 951 - 958
反应条件
potassium carbonate in nitrobenzene
T=200°C; 6 h; Yield given;
参考文献
Viswanathan, N.; Desai, Ranjit C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. <B> 20, # 4 p. 308 - 310
反应条件
caesium carbonate in acetonitrile
T=50°C; 16 h;
参考文献
Liu, Jian; Patch, Raymond J.; Schubert, Carsten; Player, Mark R.
Journal of Organic Chemistry, 2005 , vol. 70, # 24 p. 10194 - 10197
