(4S)-(-)-异丙基-5,5-二苯基-2-恶唑烷酮合成路线 （共 35 条）
反应条件
1.1: 79 percent / SOCl2 / 2 h / Heating 2.1: Mg / tetrahydrofuran 2.2: 54 percent / tetrahydrofuran / 4 h / 20 °C 3.1: 73 percent / aq. KOH / toluene / 2 h / 20 °C View Scheme
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 13 p. 1538 - 1549
参考文献
Tetrahedron Asymmetry, , vol. 10, # 6 p. 1189 - 1192
反应条件
1.1: SOCl2 / 0 - 20 °C 2.1: Mg 2.2: tetrahydrofuran / 0 - 20 °C 2.3: 53.35 g / sodium hydroxide / tetrahydrofuran / 3 h / 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 18, # 8 p. 949 - 962
反应条件
hydrogen; acetic acid; palladium on activated charcoal in methanol P=2280 Torr; 48 h;
参考文献
O'Hagan, David; Tavasli, Mustafa
Tetrahedron Asymmetry, 1999 , vol. 10, # 6 p. 1189 - 1192
反应条件
pyridine; hydrogen fluoride
T=20°C; Decarboxylation; 96 h;
参考文献
O'Hagan, David; Royer, Frederique; Tavasli, Mustafa
Tetrahedron Asymmetry, 2000 , vol. 11, # 9 p. 2033 - 2036
