N-(3-氯-4-氟苯基)-6-硝基-4-喹唑啉胺合成路线 (共 13 条)
反应条件
1.1: sodium sulfate; hydrogenchloride; hydroxylamine hydrochloride / water / 1 h / |Reflux 2.1: sulfuric acid / 1.33 h / 50 - 65 °C 3.1: hydroxylamine hydrochloride / water / 0.5 h / |Reflux 3.2: 0.5 h 4.1: trichlorophosphate / 0 - 70 °C 5.1: acetic acid / 3 h / |Reflux View Scheme
参考文献
Wang, Zheng; Wang, Cuiling; Sun, Yanni; Zhang, Ning; Liu, Zhulan; Liu, Jianli
Tetrahedron, 2014 , vol. 70, # 4 p. 906 - 913
反应条件
1: trichlorophosphate / 0 - 70 °C 2: acetic acid / 3 h / |Reflux View Scheme
参考文献
Wang, Zheng; Wang, Cuiling; Sun, Yanni; Zhang, Ning; Liu, Zhulan; Liu, Jianli
Tetrahedron, 2014 , vol. 70, # 4 p. 906 - 913
反应条件
hydrogen; nickel in tetrahydrofuran; methanol P=2585.74 Torr; 3.5 h;
参考文献
Fernandes, Celia; Oliveira, Cristina; Gano, Lurdes; Bourkoula, Athanasia; Pirmettis, Ioannis; Santos, Isabel
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 12 p. 3974 - 3980