4-甲氧基苯基氨基甲酸叔丁酯合成路线 （共 34 条）
反应条件
1: sodium hydride / tetrahydrofuran / 15 h / 0 - 20 °C
2: hydrogenchloride; water / 15 h / 20 °C
View Scheme
参考文献
Brucelle, Francois; Renaud, Philippe
Organic Letters, 2012 , vol. 14, # 12 p. 3048 - 3051
反应条件
[bis(acetoxy)iodo]benzene; silica gel; triethylamine
T=20°C; 5 h;
参考文献
Bodipati, Naganjaneyulu; Peddinti, Rama Krishna
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 23 p. 4549 - 4553
反应条件
1.1: water / 150 °C / |Green chemistry
2.1: water / 150 °C / |Green chemistry
3.1: triethylamine / dichloromethane / 0.17 h / |Inert atmosphere; |Cooling with ice
3.2: 25 °C / |Inert atmosphere; |Cooling with ice
View Scheme
参考文献
Medina-Ramos, Wilmarie; Mojica, Mike A.; Cope, Elizabeth D.; Hart, Ryan J.; Pollet, Pamela; Eckert, Charles A.; Liotta, Charles L.
Green Chemistry, 2014 , vol. 16, # 4 p. 2147 - 2155
反应条件
1.1: t-BuLi / tetrahydrofuran; pentane / 0.25 h / -78 °C
1.2: 63.74 percent / 1,2-iodoethane / tetrahydrofuran; pentane / 20 °C
2.1: 76.7 percent / Et3N / PdCl2(PPh3)4; CuI / 1 h / 20 °C
3.1: 62 percent / HgSO4 / H2O; CH2Cl2 / 4 h / 42 °C
View Scheme
参考文献
Amiet, Gary; Huegel, Helmut M.; Nurlawis, Faizul
Synlett, 2002 , # 3 p. 495 - 497
