1-(2-羟基-4-甲氧基苯基)-2-苯乙酮合成路线 （共 33 条）
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran T=20°C; Mitsunobu reaction; 0.0833333 h;
参考文献
Brueggemeier, Robert W.; Kim, Young-Woo; Hackett, John C.
Patent: US2006/183923 A1, 2006 ;
Location in patent: Page/Page column 6 ;
反应条件
boron trifluoride diethyl etherate T=85°C; Acylation; Friedel Crafts; 1.5 h;
参考文献
Balasubramanian, Sreenivasan; Nair, Muraleedharan G.
Synthetic Communications, 2000 , vol. 30, # 3 p. 469 - 484
反应条件
potassium carbonate in acetone T=35 - 40°C; 4 h;
参考文献
Jain, A. C.; Paliwal, Poonam
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 985 - 988
反应条件
PPA; Polyphosphoric acid (PPA) T=95°C; 0.5 h;
参考文献
Verma, Braham S.; Dhindsa, Kuldip Singh; Sangwan, Naresh K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 2 p. 239 - 243
反应条件
potassium carbonate; benzene
参考文献
Kanagalakshmi, Kanagasabai; Premanathan, Mariappan; Priyanka, Ragunathan; Hemalatha, Balasubramanian; Vanangamudi, Arumugasamy
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 6 p. 2447 - 2452
反应条件
1: 77 percent / BF3*OEt2 / 2 h / 100 °C 2: 88 percent / PPh3; DIAD / tetrahydrofuran / 0.08 h / 20 °C View Scheme
参考文献
Kim, Young-Woo; Brueggemeier, Robert W
Tetrahedron Letters, 2002 , vol. 43, # 35 p. 6113 - 6115
反应条件
1: 77 percent / BF3*OEt2 / 2 h / 100 °C 2: 88 percent / PPh3; DIAD / tetrahydrofuran / 0.08 h / 20 °C View Scheme
参考文献
Beger, J.; Binte, H.-J.; Brunne, L.; Neumann, R.
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1992 , vol. 334, # 3 p. 269 - 277
反应条件
1: AlCl3 / 1,2-dichloro-ethane / 5 h / 65 °C 2: K2CO3 / acetone / 20 h / Heating View Scheme
参考文献
Beger, J.; Binte, H.-J.; Brunne, L.; Neumann, R.
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1992 , vol. 334, # 3 p. 269 - 277
反应条件
potassium carbonate in acetone 20 h; Heating;
参考文献
Beger, J.; Binte, H.-J.; Brunne, L.; Neumann, R.
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1992 , vol. 334, # 3 p. 269 - 277
反应条件
hydrogenchloride; acetic acid
参考文献
Kawase
Bulletin of the Chemical Society of Japan, 1958 , vol. 31, p. 390,392
