1-环己烯基-1-甲酸甲酯合成路线 （共 62 条）
反应条件
1: sodium; ethanol 2: PCl5; benzene / 0 °C / Behandlung des gebildeten 1-Chlormethyl-cyclohexens-(1) (Kp: 77grad) mit Magnesium und Aethylbromid in Aether und Kochen der erhaltenen Loesung mit Paraformaldehyd View Scheme
参考文献
Mousseron; Nguyen Phuoc Du
Bulletin de la Societe Chimique de France, 1948 , p. 91,92
反应条件
D-glucose; cytochrome P450-BM3mutant V78L/A82F/F87A from Bacillus megaterium; NADPH pH=7.4; Enzymatic reaction;
参考文献
Agudo, Ruben; Reetz, Manfred T.
Chemical Communications, 2013 , vol. 49, # 93 p. 10914 - 10916
反应条件
hydrogenchloride; sodium borohydride in diethyl ether; ethanol
参考文献
HER MAJESTY THE QUEEN IN RIGHT OF NEW ZEALAND,DEPARTMENT OF SCIENTIFIC AND INDUSTRIAL RESEARCH,CHEMISTRY DIVISON
Patent: EP302599 A2, 1989 ;
反应条件
1: 34 percent / CrO3 / acetic acid 2: 60 percent / H2 / Pd/C / methanol 3: 60 percent / H2O, K2CO3 / methanol View Scheme
参考文献
Bugg, Timothy D. H.; Abell, Chris; Coggins, John R.
Tetrahedron Letters, 1988 , vol. 29, # 51 p. 6779 - 6782
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene Heating;
参考文献
Journal of Organic Chemistry, , vol. 67, # 17 p. 6268 - 6271
反应条件
sodium methylate in methanol
T=100°C; Equilibrium constantThermodynamic data;
参考文献
Rhoads,S.J. et al.
Journal of Organic Chemistry, 1970 , vol. 35, # 10 p. 3352 - 3358
反应条件
1: 82 percent / vitride / tetrahydrofuran / 0 °C
2: 90 percent / N,N-diisopropylethylamine / CH2Cl2 / 2 h / Ambient temperature
View Scheme
参考文献
Kawaji, Tsuyoshi; Shohji, Noriaki; Miyashita, Kenji; Okamoto, Sentaro
Chemical Communications, 2011 , vol. 47, # 27 p. 7857 - 7859
反应条件
1.1: 99 percent / LiAlH4 / diethyl ether / 20 °C
2.1: 55 percent / Me3SiCl / CCl4 / 2 h / 20 °C
3.1: Li / 4,4'-di-tert-butylbiphenyl / tetrahydrofuran / 1 h / 0 °C
3.2: 78 percent / H2O / tetrahydrofuran / 0 - 20 °C
View Scheme
参考文献
Macia, Beatriz; Gomez, Cecilia; Yus, Miguel
Tetrahedron Letters, 2005 , vol. 46, # 36 p. 6101 - 6104
反应条件
diisobutylaluminium hydride in diethyl ether
1.) -70 deg C, 1 h, 2.) -70 -> -30 deg C, 1 h;
参考文献
Macia, Beatriz; Gomez, Cecilia; Yus, Miguel
Tetrahedron Letters, 2005 , vol. 46, # 36 p. 6101 - 6104
反应条件
lithium aluminium tetrahydride; phosphorus tribromide
Yield given. Multistep reaction;
参考文献
Kitamura, Tsuyoshi; Kuzuba, Yuichi; Sato, Yoshihiro; Wakamatsu, Hideaki; Fujita, Reiko; Mori, Miwako
Tetrahedron, 2004 , vol. 60, # 34 p. 7375 - 7389
