(3R,4R)-二氢-3,4-二羟基-3-甲基-2(3H)-呋喃酮合成路线 （共 13 条）
反应条件
1: 96 percent / LiAlH4 / tetrahydrofuran / 60 °C
2: 99 percent / TBAF; AcOH / tetrahydrofuran / 0 - 20 °C
3: 89 percent / CrO3; pyridine; Ac2O / CH2Cl2 / 20 °C
4: 95 percent / TFA / H2O / 0 - 20 °C
View Scheme
参考文献
Koumbis, Alexandros E.; Kaitaidis, Apostolos D.; Kotoulas, Stefanos S.
Tetrahedron Letters, 2006 , vol. 47, # 48 p. 8479 - 8481
反应条件
1: 89 percent / CrO3; pyridine; Ac2O / CH2Cl2 / 20 °C
2: 95 percent / TFA / H2O / 0 - 20 °C
View Scheme
参考文献
Koumbis, Alexandros E.; Kaitaidis, Apostolos D.; Kotoulas, Stefanos S.
Tetrahedron Letters, 2006 , vol. 47, # 48 p. 8479 - 8481
反应条件
1: 90 percent / pyridine / 20 °C
2: 98 percent / imidazole / CH2Cl2 / 20 °C
3: 96 percent / LiAlH4 / tetrahydrofuran / 60 °C
4: 99 percent / TBAF; AcOH / tetrahydrofuran / 0 - 20 °C
5: 89 percent / CrO3; pyridine; Ac2O / CH2Cl2 / 20 °C
6: 95 percent / TFA / H2O / 0 - 20 °C
View Scheme
参考文献
Koumbis, Alexandros E.; Kaitaidis, Apostolos D.; Kotoulas, Stefanos S.
Tetrahedron Letters, 2006 , vol. 47, # 48 p. 8479 - 8481
