RhCl3 hydrate; 1,3-bis-(diphenylphosphino)propane in diethylene glycol dimethyl ether T=200°C; 1.33333 h; Microwave irradiation;

palladium (II) trifluoroacetate; (R)-2,2'-di[4(S)-iPr-4,5-dihydrooxazol-2-yl]-1,1'-binaphthyl; p-benozquinone in tetrachloroethane, 1,1,2,2- T=60°C; Wacker-type cyclization; 24 h; DarknessInert atmosphere;

1.1: lithium powder; 4,4'-di-tert-butylbiphenyl / tetrahydrofuran / 0.75 h / 0 °C 1.2: tetrahydrofuran / 0.25 h / -78 °C 1.3: 45 percent / water / tetrahydrofuran / -78 - 20 °C 2.1: 60 percent / phosphoric acid / toluene / 4 h / 110 °C View Scheme

1.1: lithium powder; 4,4'-di-tert-butylbiphenyl / tetrahydrofuran / 0.75 h / 0 °C 1.2: tetrahydrofuran / 0.25 h / -78 °C 1.3: 45 percent / water / tetrahydrofuran / -78 - 20 °C 2.1: 60 percent / phosphoric acid / toluene / 4 h / 110 °C View Scheme

palladium (II) trifluoroacetate; p-benozquinone; (-)-sparteine in tetrachloroethane, 1,1,2,2- T=60°C; Wacker-type cyclization; 24 h; DarknessInert atmosphere;

1: 91 percent / thionyl chloride, pyridine / benzene / 1 h / Heating 2: 90 percent / dimethylformamide / 0.5 h / Heating 3: 71 percent / DIBALH / diethyl ether; cyclohexane / 1.) -78 deg C, 30 min, 2.) RT, 3 h 4: 1.) BuLi / 1.) ether, hexane, 2 h, 2.) ether, a) 1 h, b) reflux, 4 h View Scheme

1: 71 percent / DIBALH / diethyl ether; cyclohexane / 1.) -78 deg C, 30 min, 2.) RT, 3 h 2: 1.) BuLi / 1.) ether, hexane, 2 h, 2.) ether, a) 1 h, b) reflux, 4 h View Scheme

n-butyllithium 1.) ether, hexane, 2 h, 2.) ether, a) 1 h, b) reflux, 4 h; Yield given. Multistep reaction;