1: HCl gas / ethyl acetate / 48 h / -10 °C 2: 1.) KOH; 2.) 1M HCl / H2O; methanol / 3 h / Ambient temperature View Scheme

1: 40 percent / CaSO4, 4 Angstroem molecular sieves, Hg(CN)2 / toluene / 2 h / Heating 2: HCl gas / ethyl acetate / 48 h / -10 °C 3: 1.) KOH; 2.) 1M HCl / H2O; methanol / 3 h / Ambient temperature View Scheme

1: Et3N / dimethylformamide / 85 °C 2: 1.) 3-chloroperbenzoic acid; 2.) citric acid / 1.) CH2Cl2; 2.) MeOH 3: 40 percent / CaSO4, 4 Angstroem molecular sieves, Hg(CN)2 / toluene / 2 h / Heating 4: HCl gas / ethyl acetate / 48 h / -10 °C 5: 1.) KOH; 2.) 1M HCl / H2O; methanol / 3 h / Ambient temperature View Scheme

1: 60 percent / 4-(dimethylamino)pyridine / ethyl acetate / Heating 2: HCl gas / ethyl acetate / 48 h / -10 °C 3: 1.) KOH; 2.) 1M HCl / H2O; methanol / 3 h / Ambient temperature View Scheme

1: HCl gas / ethyl acetate / 48 h / -10 °C 2: 1.) KOH; 2.) 1M HCl / H2O; methanol / 3 h / Ambient temperature View Scheme

1: 1.) 3-chloroperbenzoic acid; 2.) citric acid / 1.) CH2Cl2; 2.) MeOH 2: 40 percent / CaSO4, 4 Angstroem molecular sieves, Hg(CN)2 / toluene / 2 h / Heating 3: HCl gas / ethyl acetate / 48 h / -10 °C 4: 1.) KOH; 2.) 1M HCl / H2O; methanol / 3 h / Ambient temperature View Scheme

1: 4-(dimethylamino)pyridine / CHCl3 2: Et3N / dimethylformamide / 85 °C 3: 1.) 3-chloroperbenzoic acid; 2.) citric acid / 1.) CH2Cl2; 2.) MeOH 4: 40 percent / CaSO4, 4 Angstroem molecular sieves, Hg(CN)2 / toluene / 2 h / Heating 5: HCl gas / ethyl acetate / 48 h / -10 °C 6: 1.) KOH; 2.) 1M HCl / H2O; methanol / 3 h / Ambient temperature View Scheme

hydrogenchloride; ethyl acetate Behandeln mit wss. Natronlauge und Erwaermen der mit Salzsaeure angesaeuerten Loesung;

water T=37°C; pH=7.4; aq. phosphate buffer; Kinetics;