1-[2-[4-(3,4-二氢-6-甲氧基-2-苯基-1-萘基)苯氧基]乙基]吡咯烷盐酸盐合成路线 (共 3 条)
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; water 18 h; Heating / reflux;
参考文献
US2005/70512 A1, ;
Page/Page column 23 ;
反应条件
hydrogenchloride in dichloromethane; di-isopropyl ether; ethyl acetate 2 h;
参考文献
WO2010/125578 A2, ;
Page/Page column 20; 21 ;
反应条件
hydrogenchloride in tetrahydrofuran; diethyl ether; dichloromethane; water; ethyl acetate