1-苄基-3-氨基吡咯烷合成路线 （共 19 条）
参考文献
Warner-Lambert Company
Patent: US4617308 A1, 1986 ;
参考文献
Warner-Lambert Company
Patent: US4604401 A1, 1986 ;
反应条件
hydrogen; 5 palladium over charcoal in water T=60°C; 10 h; Product distribution / selectivity;
参考文献
Toray Fine Chemicals Co., Ltd.
Patent: EP1640364 A1, 2006 ;
Location in patent: Page/Page column 10 ;
反应条件
sodium hydroxide; acetic anhydride in dichloromethane
参考文献
KANEBO, LTD.
Patent: EP286089 B1, 1991 ;
反应条件
sodium hydroxide; acetic anhydride; palladium on charcoal in tetrahydrofuran; methanol; dichloromethane; water; acetic acid
参考文献
Warner-Lambert Company
Patent: US4771054 A1, 1988 ;
反应条件
chloroformic acid ethyl ester; triethylamine
1.) DMF, 0 deg C, 30 min, 2.) room temp.; Yield given. Multistep reaction;
参考文献
Dostert; Imbert; Ancher; et al.
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444
参考文献
Yamanouchi Pharmaceutical Co., Ltd.
Patent: US4197243 A1, 1980 ;
反应条件
in dichloromethane
2 h; Ambient temperature; Yield given;
参考文献
Iwanami; Takashima; Hirata; Hasegawa; Usuda
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1224 - 1230
反应条件
in dichloromethane
T=0 - 20°C;
参考文献
Shanghai Institute of Pharmaceutical Industry; Jiangsu Chia Tai Tianqing Pharmaceutical Co., Ltd.
Patent: EP2292613 A1, 2011 ;
Location in patent: Page/Page column 22 ;
