(-)-alpha-乙基-3,5-二(三氟甲基)-苯甲醇合成路线 （共 4 条）
反应条件
1: in tetrahydrofuran T=0°C; 0.5 h; 2: With hydrogenchloride; water in tetrahydrofuran pH=< 7;
参考文献
KOWA COMPANY, LTD.
Patent: US2009/82352 A1, 2009 ;
Location in patent: Page/Page column 29 ;
US 20090082352 A1
参考文献
Bloom, Jonathan D.; Dushin, Russell G.; Curran, Kevin J.; Donahue, Fran; Norton, Emily B.; Terefenko, Eugene; Jones, Thomas R.; Ross, Adma A.; Feld, Boris; Lang, Stanley A.; DiGrandi, Martin J.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 13 p. 3401 - 3406
反应条件
chromium(VI) oxide; sulfuric acid Jones oxidation;
参考文献
Bloom, Jonathan D.; Dushin, Russell G.; Curran, Kevin J.; Donahue, Fran; Norton, Emily B.; Terefenko, Eugene; Jones, Thomas R.; Ross, Adma A.; Feld, Boris; Lang, Stanley A.; DiGrandi, Martin J.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 13 p. 3401 - 3406
反应条件
1: CrO3; aq. H2SO4
2: pyridine / ethanol
3: NaBH4; ZrCl4
View Scheme
参考文献
Bloom, Jonathan D.; Dushin, Russell G.; Curran, Kevin J.; Donahue, Fran; Norton, Emily B.; Terefenko, Eugene; Jones, Thomas R.; Ross, Adma A.; Feld, Boris; Lang, Stanley A.; DiGrandi, Martin J.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 13 p. 3401 - 3406
