1: 93 percent / butyllithium / hexane; diethyl ether / 0.25 h / -75 °C 2: 97 percent / potassium hydroxide / ethanol; H2O / 2 h / Heating View Scheme

potassium fluoride in tetrahydrofuran; water 2 h; Heating;

1: 93 percent / potassium fluoride / tetrahydrofuran; H2O / 2 h / Heating 2: 96 percent / 2,2,6,6-tetramethylpiperidine; butyllithium / tetrahydrofuran; hexane / 2 h / -75 °C View Scheme

n-butyllithium in diethyl ether; hexane T=-75°C; 0.25 h;