反应条件
1: With N-bromosuccinmide; water; acetic acid in 1,4-dioxane T=0 - 20°C; 4 h; 2: With sodium hydroxide in 1,4-dioxane; water T=20°C;
参考文献
METABOLIC SOLUTIONS DEVELOPMENT COMPANY; COLCA, Gerard, R.; LARSEN, Scott, D.; TANIS, Steven, P.; PARKER, Timothy; GADWOOD, Robert
Patent: WO2010/105048 A1, 2010 ;
Location in patent: Page/Page column 60 ;
WO 2010/105048 A1