萘-1,3,6,8-四酚合成路线 （共 18 条）
反应条件
1: 69 percent / BzNEt3Cl / CHCl3; H2O
2: 92 percent / Ba(OH)2 / dioxane; H2O
3: diethyl ether
4: 99 percent / 60percent HClO4 / H2O; acetic acid
5: 97 percent / H2 / Pd/C (5percent) / ethyl acetate; ethanol
6: CH3ONa / methanol
View Scheme
参考文献
Ichinose, Koji; Ebizuka, Yutaka; Sankawa, Ushio
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2873 - 2875
反应条件
palladium on activated charcoal; hydrogen; acetic acid in ethanol
参考文献
Vagstad, Anna L.; Hill, Eric A.; Labonte, Jason W.; Townsend, Craig A.
Chemistry and Biology, 2012 , vol. 19, # 12 p. 1525 - 1534
反应条件
sodium methylate in methanol
参考文献
Baker,P.M.; Bycroft,B.W.
Chemical Communications (London), 1968 , p. 71 - 72
反应条件
potassium phosphate; NADP in water
T=30°C; Pyricularia oryzae naphthol reductase; influence of pH and of (+)scytalone concentration; Kinetics;
参考文献
Viviani, F.; Vors, J. P.; Gaudry, M.; Marquet, A.
Bulletin de la Societe Chimique de France, 1993 , vol. 130, # 3 p. 395 - 404
反应条件
1.1: MeONa / methanol / 0.33 h / 60 °C
1.2: 25 percent / NaBH4 / methanol / 4 h / 60 °C
2.1: 76 percent / 1N NaOH / 3 h / 45 °C
View Scheme
参考文献
Simpson, Thomas J.; Weerasooriya, M. K. Bandumathie
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 2000 , # 16 p. 2771 - 2776
反应条件
oxygen; potassium carbonate in N,N-dimethyl-formamide
T=25°C; 10 h;
参考文献
Snyder, Scott A.; Tang, Zhen-Yu; Gupta, Ritu
Journal of the American Chemical Society, 2009 , vol. 131, p. 5744 - 5745
反应条件
sodium tetrahydroborate in methanol
参考文献
Ichinose, Koji; Ebizuka, Yutaka; Sankawa, Ushio
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2873 - 2875
反应条件
sodium tetrahydroborate; sodium methylate in methanol
Mechanism;
参考文献
Ichinose, Koji; Ebizuka, Yutaka; Sankawa, Ushio
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 10 p. 2873 - 2875
