potassium hydroxide in water T=80°C; 3.5 h;

potassium hydroxide in water T=100°C; 16 h;

carbon disulfide in potassium hydroxide; hexane; water

Birman's catalyst; methanol; benzoic acid in toluene T=20°C; 24 h; Resolution of racemate; Reagent/catalystSolvent; enantioselective reaction;

Birman's catalyst; methanol; benzoic acid in chloroform-d1 T=20°C; 12 h; Resolution of racemate; enantioselective reaction;

in tetrahydrofuran T=80°C; 0.333333 h;

1: (S)-1-phenyl-2-hydroxyethylamine With sulfuric acid T=0°C; 2 h; 2: potassium ethylxanthate With sodium hydroxide; sulfuric acid T=50°C; pH=9; 9 h;

1: (rac)-4-phenyl-1,3-thiazolidine-2-thione With Birman's catalyst; N-ethyl-N,N-diisopropylamine in chloroform T=23°C; Resolution of racemate; 2: isobutyric anhydride With sodium sulfate in chloroform T=23°C; 4 h; Resolution of racemate; enantioselective reaction;

1: formic acid / water 2: potassium hydroxide; (S)-N-(4-bromobenzyl)-N,N,3,3-tetramethyl-2-(3-(4-nitrophenyl)thioureido)butan-1-ammonium acetate / dichloromethane / 8 h / -30 °C / |Inert atmosphere 3: sodium nitrite; acetic acid / dimethyl sulfoxide / 24 h / 40 °C 4: trifluoroacetic acid / dichloromethane / 24 h 5: sodium tetrahydroborate; iodine / tetrahydrofuran / 19 h / 0 °C / |Reflux 6: triethylamine / dimethyl sulfoxide / 2 h / 100 °C / |Irradiation View Scheme

1: potassium hydroxide; (S)-N-(4-bromobenzyl)-N,N,3,3-tetramethyl-2-(3-(4-nitrophenyl)thioureido)butan-1-ammonium acetate / dichloromethane / 8 h / -30 °C / |Inert atmosphere 2: sodium nitrite; acetic acid / dimethyl sulfoxide / 24 h / 40 °C 3: trifluoroacetic acid / dichloromethane / 24 h 4: sodium tetrahydroborate; iodine / tetrahydrofuran / 19 h / 0 °C / |Reflux 5: triethylamine / dimethyl sulfoxide / 2 h / 100 °C / |Irradiation View Scheme