1: 70 percent / LDA / tetrahydrofuran / -78 °C 2: 88 percent / PPTS / methanol / 36 h / Ambient temperature 3: 96 percent / 2,6-lutidine / CH2Cl2 / -78 °C 4: 82 percent / CSA / methanol; CH2Cl2 / 5 h / 0 °C 5: 79 percent / PDC / dimethylformamide / 36 h / Ambient temperature 6: 80 percent / DCC, 4-DMAP / CH2Cl2 / 12 h / Ambient temperature 7: 94 percent / <RuCHPh>Cl2*(PCy3)2 / CH2Cl2 / 12 h / Ambient temperature 8: 65 percent / HF / acetonitrile; diethyl ether / 12 h / Ambient temperature 9: 48 percent / dimethyl dioxirane / CH2Cl2 / 2 h / -35 °C View Scheme

1: LDA / tetrahydrofuran / 1.) -78 deg C, 1 h, 2.) -78 deg C, 15 min 2: 86 percent / PPTS / methanol / 72 h / Ambient temperature 3: 95 percent / 2,6-lutidine / CH2Cl2 / 2 h / 0 °C View Scheme

1.1: LDA / hexane; tetrahydrofuran / 1.5 h / -78 °C 1.2: 70 percent / hexane; tetrahydrofuran / 2 h / -78 °C 2.1: 85 percent / PPTS / methanol / 14 h / 20 °C 3.1: 92 percent / 2,6-lutidine / CH2Cl2 / 3.75 h / -78 - 20 °C 4.1: 78 percent / camphorsulfonic acid / CH2Cl2; methanol / 4 h / 0 °C 5.1: 83 percent / PDC / dimethylformamide / 36 h / 20 °C 6.1: 81 percent / DCC; DMAP / CH2Cl2 / 14 h / 20 °C 7.1: 80 percent / CH2Cl2 / [Mo{(t-Bu)(3,5-dimethylphenyl)N}3] / toluene / 8 h / 80 °C 8.1: 99 percent / quinoline; H2 / Lindlar catalyst / hexane; CH2Cl2 / 8 h / 20 °C 9.1: 79 percent / aq. HF / acetonitrile; diethyl ether / 8 h / 20 °C View Scheme