雌三醇-16beta-D-葡糖苷酸合成路线 (共 12 条)
反应条件
sodium hydroxide in methanol 24 h; Ambient temperature;
参考文献
Wu, Yinqiu; Blackwell, Leonard F.
Steroids, 1993 , vol. 58, # 10 p. 452 - 456
反应条件
magnesium chloride in aq. phosphate buffer; dimethyl sulfoxide T=37°C; pH=7.4; Enzymatic reaction; regioselective reaction;
参考文献
Drug Metabolism and Disposition, , vol. 41, # 3 p. 582 - 591
反应条件
magnesium chloride in aq. phosphate buffer; dimethyl sulfoxide T=37°C; pH=7.4; Enzymatic reaction; regioselective reaction;
参考文献
Drug Metabolism and Disposition, , vol. 41, # 3 p. 582 - 591
反应条件
1: 82 percent 2: 93 percent / pyridine / 40 h / Ambient temperature 3: 97 percent / aq. AcOH / tetrahydrofuran / 40 h / Ambient temperature 4: 80 percent / CdCO3 / toluene / 2.5 h / Heating 5: 65 percent / aq. NaOH / methanol / 24 h / Ambient temperature View Scheme
参考文献
Steroids, , vol. 58, # 10 p. 452 - 456
反应条件
1: 93 percent / pyridine / 40 h / Ambient temperature 2: 97 percent / aq. AcOH / tetrahydrofuran / 40 h / Ambient temperature 3: 80 percent / CdCO3 / toluene / 2.5 h / Heating 4: 65 percent / aq. NaOH / methanol / 24 h / Ambient temperature View Scheme
参考文献
Steroids, , vol. 58, # 10 p. 452 - 456
反应条件
1: 80 percent / CdCO3 / toluene / 2.5 h / Heating 2: 65 percent / aq. NaOH / methanol / 24 h / Ambient temperature View Scheme
参考文献
Steroids, , vol. 58, # 10 p. 452 - 456
反应条件
1: 97 percent / aq. AcOH / tetrahydrofuran / 40 h / Ambient temperature 2: 80 percent / CdCO3 / toluene / 2.5 h / Heating 3: 65 percent / aq. NaOH / methanol / 24 h / Ambient temperature View Scheme
参考文献
Steroids, , vol. 58, # 10 p. 452 - 456
反应条件
1: 80 percent / CdCO3 / toluene / 2.5 h / Heating 2: 65 percent / aq. NaOH / methanol / 24 h / Ambient temperature View Scheme
参考文献
Steroids, , vol. 58, # 10 p. 452 - 456
反应条件
magnesium chloride in aq. phosphate buffer; dimethyl sulfoxide T=37°C; pH=7.4; Enzymatic reaction; regioselective reaction;
参考文献
Drug Metabolism and Disposition, , vol. 41, # 3 p. 582 - 591
反应条件
β-glucoronidase II in water T=37°C; 0.166667 h; substrate specifity of enzyme; Product distribution;
参考文献
Ogushi, Susumu; Koga, Satoshi; Ito, Kiyoshi; Makino, Yasutaka; Ando, Makoto; Tsuru, Daisuke
Agricultural and Biological Chemistry, 1986 , vol. 50, # 12 p. 3093 - 3100