N-(叔丁氧羰基)-5-甲氧基-2-硝基苯胺合成路线 (共 5 条)
反应条件
sodium methylate in methanol; toluene
参考文献
Sankyo Company, Limited
Patent: EP1191019 A1, 2002 ;
Location in patent: Page 55 ;
反应条件
1: 2-nitro-5-methoxy aniline With sodium hydride in tetrahydrofuran T=0 - 20°C; 1.16667 h; 2: di-tert-butyl dicarbonate in tetrahydrofuran T=20°C; 2 h;
参考文献
Sumitomo Chemical Company, Limited
Patent: EP1172356 A1, 2002 ;
Location in patent: Page 8 ;
反应条件
diphenyl-phosphinic acid; triethylamine Cutrius rearrangement; 16 h; Heating;
参考文献
Hay, Michael P.; Gamage, Swarna A.; Kovacs, Mary S.; Pruijn, Frederik B.; Anderson, Robert F.; Patterson, Adam V.; Wilson, William R.; Brown, J. Martin; Denny, William A.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 169 - 182
反应条件
palladium monocarbide
参考文献
Adam, Geo; Goetschi, Erwin; Wichmann, Juergen; Woltering, Thomas Johannes
Patent: US2003/166639 A1, 2003 ;
US 20030166639 A1
反应条件
hydrogenchloride in methanol T=20°C; 96 h;
参考文献
Hay, Michael P.; Gamage, Swarna A.; Kovacs, Mary S.; Pruijn, Frederik B.; Anderson, Robert F.; Patterson, Adam V.; Wilson, William R.; Brown, J. Martin; Denny, William A.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 169 - 182