hydrogen; palladium on activated charcoal in ethyl acetate T=20°C; 7305 h;

hydrogen; platinum on activated charcoal in isopropyl alcohol Catalytic hydrogenation; P=7600 Torr; 1.5 h;

palladium 10 on activated carbon; hydrogen in methanol T=20°C; P=3040.2 Torr; 2 h;

1: With sodium hypochlorite; sodium chlorite; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical in water; acetonitrile T=35°C; pH=6.7; 7 h; Inert atmosphereaq. phosphate buffer; 2: With sodium hydrogencarbonate; sodium sulfite in water; acetonitrile T=0°C; pH=8; Inert atmosphere; 3: With hydrogenchloride in water pH=2; Inert atmosphere;

tetra(n-butyl)ammonium hydroxide; dihydrogen peroxide in ethylene glycol dimethyl ether; water T=-20°C; 0.833333 h;

ammonium cerium(IV) nitrate in water; acetonitrile T=0°C; 1 h;

hydrogenchloride; water; acetic acid T=130°C; 10 h;

1.1: LDA / tetrahydrofuran; hexane / 0.5 h / -78 °C 1.2: 85.3 percent / LiI / tetrahydrofuran; hexane; various solvent(s) / 3.5 h / -78 - -30 °C 2.1: 89.6 percent / 2-methyl-2-butene; H2O2; tetrabutylammonium hydroxide / 1,2-dimethoxy-ethane; H2O / 0.17 h / -10 °C 3.1: 94.6 percent / H2 / Pt/C / propan-2-ol / 2.5 h / 3800 Torr View Scheme

1: 100 percent / H2 / Pd/C / ethyl acetate; methanol / 1 h 2: 59.3 percent / aq. H2O2; tetrabutylammonium hydroxide / tetrahydrofuran / 0.83 h / -20 °C View Scheme

1.1: 98.6 percent / Et3N; 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 0 °C 2.1: LDA / tetrahydrofuran; hexane / 0.5 h / -78 °C 2.2: 85.3 percent / LiI / tetrahydrofuran; hexane; various solvent(s) / 3.5 h / -78 - -30 °C 3.1: 89.6 percent / 2-methyl-2-butene; H2O2; tetrabutylammonium hydroxide / 1,2-dimethoxy-ethane; H2O / 0.17 h / -10 °C 4.1: 94.6 percent / H2 / Pt/C / propan-2-ol / 2.5 h / 3800 Torr View Scheme