1.1: hydrogen / ethanol / 3 h / 760.05 Torr / Inert atmosphere 1.2: Inert atmosphere 2.1: sodium chlorite; sodium hypochlorite; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical / water; acetonitrile / 7 h / 35 °C / pH 6.7 / Inert atmosphere; aq. phosphate buffer 2.2: 0 °C / pH 8 / Inert atmosphere 2.3: pH 2 / Inert atmosphere View Scheme

1.1: (5R)-5-benzyl-2,2,3-trimethyl imidazolidin-4-one; sodium dihydrogenphosphate; benzoic acid / water; acetonitrile / 24 h / 0 °C / Inert atmosphere 2.1: sodium tetrahydroborate / methanol / 0.5 h / 0 °C / Inert atmosphere 3.1: sodium hydride / tetrahydrofuran; mineral oil / 0 °C / Inert atmosphere 3.2: 18 h / 20 °C / Inert atmosphere 4.1: n-butyllithium / tetrahydrofuran; hexane / 0 °C / Inert atmosphere 4.2: 0.08 h / Inert atmosphere 5.1: hydrogen / ethanol / 3 h / 760.05 Torr / Inert atmosphere 5.2: Inert atmosphere 6.1: sodium chlorite; sodium hypochlorite; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical / water; acetonitrile / 7 h / 35 °C / pH 6.7 / Inert atmosphere; aq. phosphate buffer 6.2: 0 °C / pH 8 / Inert atmosphere 6.3: pH 2 / Inert atmosphere View Scheme