3-羟基螺[茚满-1,4’-哌啶]-1’-甲酸叔丁酯合成路线

3-羟基螺[茚满-1,4’-哌啶]-1’-甲酸叔丁酯合成路线（共 3 条）

137419-24-01H-螺[茚-1,4-哌啶]-1-羧酸叔丁酯

185525-42-23-羟基螺[茚满-1,4’-哌啶]-1’-甲酸叔丁酯

参考文献

AMIRA PHARMACEUTICALS, INC
Patent: WO2009/61681 A2, 2009 ;
Location in patent: Page/Page column 65 ;
WO 2009/061681 A2

185525-42-23-羟基螺[茚满-1,4’-哌啶]-1’-甲酸叔丁酯

参考文献

F. HOFFMANN-LA ROCHE AG
Patent: WO2008/68159 A1, 2008 ;
Location in patent: Page/Page column 28; 29 ;
WO 2008/068159 A1

137419-24-01H-螺[茚-1,4-哌啶]-1-羧酸叔丁酯

185525-42-23-羟基螺[茚满-1,4’-哌啶]-1’-甲酸叔丁酯+

189149-23-3

参考文献

Tata, James R.; Nargund, Ravi P.; Murphy, Marcia M.; Johnston, David B. R.; Patchett, Arthur A.; Cheng, Kang; Wei, Liente; Chan, Wanda W.-S.; Butler, Bridget; Jacks, Thomas M.; Hickey, Gerard; Smith, Roy
Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 6 p. 663 - 668