(R)-2-甲基琥珀酸-4-叔丁酯合成路线 （共 13 条）
反应条件
1: 33 percent / aq. lithium bromide / dimethylformamide / 8 h / 135 °C 2: alcalase; aq. NaOH / acetone / 18 h View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 17 p. 3285 - 3295
反应条件
sodium hydroxide; Alcalase in acetone Hydrolysis; 18 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 10, # 17 p. 3285 - 3295
反应条件
1: 97 percent / BH3*SMe2 / tetrahydrofuran / 24 h 2: 99 percent / pTsOH*H2O / CH2Cl2 / 4 h 3: 93 percent / LiAlH4 / diethyl ether / 4 h / 20 °C 4: pyridine / 18 h / 0 °C 5: 98 percent / LiAlH4 / diethyl ether / 4 h / 20 °C 6: 57 percent / p-toluenesulfonic acid monohydrate / methanol / 3 h / Heating View Scheme
参考文献
Tashiro, Takuya; Mori, Kenji
European Journal of Organic Chemistry, 1999 , # 9 p. 2167 - 2173
