1,2,3,4-四氢-2-喹啉乙酸合成路线 （共 8 条）
反应条件
1: H2 / PtO2 / methanol 2: SOCl2 3: LiAlH4 / tetrahydrofuran 4: I2, PPh3, imidazole / toluene; acetonitrile 5: dimethylformamide 6: 12N aq. HCl View Scheme
参考文献
Katayama, Seiji; Ae, Nobuyuki; Nagata, Ryu
Tetrahedron Asymmetry, 1998 , vol. 9, # 24 p. 4295 - 4299
反应条件
1: 42 percent / Ac2O / 9 h / 40 °C 2: 90 percent / HCl, H2O / 0.17 h 3: 76 percent / H2 / PtO2 / methanol / 3 h / 760 Torr 4: 91 percent / KOH, H2O / methanol / 12 h View Scheme
参考文献
Gilchrist, Thomas L.; Rahman, Adrian
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 7 p. 1203 - 1207
反应条件
1: 76 percent / H2 / PtO2 / methanol / 3 h / 760 Torr 2: 91 percent / KOH, H2O / methanol / 12 h View Scheme
参考文献
Gilchrist, Thomas L.; Rahman, Adrian
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 7 p. 1203 - 1207
反应条件
1: I2, PPh3, imidazole / toluene; acetonitrile 2: dimethylformamide 3: 12N aq. HCl View Scheme
参考文献
Katayama, Seiji; Ae, Nobuyuki; Nagata, Ryu
Tetrahedron Asymmetry, 1998 , vol. 9, # 24 p. 4295 - 4299
反应条件
1: SOCl2 2: LiAlH4 / tetrahydrofuran 3: I2, PPh3, imidazole / toluene; acetonitrile 4: dimethylformamide 5: 12N aq. HCl View Scheme
参考文献
Katayama, Seiji; Ae, Nobuyuki; Nagata, Ryu
Tetrahedron Asymmetry, 1998 , vol. 9, # 24 p. 4295 - 4299
反应条件
1: LiAlH4 / tetrahydrofuran 2: I2, PPh3, imidazole / toluene; acetonitrile 3: dimethylformamide 4: 12N aq. HCl View Scheme
参考文献
Katayama, Seiji; Ae, Nobuyuki; Nagata, Ryu
Tetrahedron Asymmetry, 1998 , vol. 9, # 24 p. 4295 - 4299
反应条件
1: 81 percent / LDA / diethyl ether / 0.17 h / -60 °C 2: 65 percent / KOH, H2O, Ni-Al alloy / methanol / 18 h View Scheme
参考文献
Gilchrist, Thomas L.; Rahman, Adrian
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 7 p. 1203 - 1207
参考文献
Katayama, Seiji; Ae, Nobuyuki; Nagata, Ryu
Tetrahedron Asymmetry, 1998 , vol. 9, # 24 p. 4295 - 4299
