1-[2-(甲基氨基)苯基]乙酮合成路线 （共 15 条）
反应条件
1: 1) p-TsOH, 2) H2, Raney nickel / 1) toluene, reflux, 2) EtOH, 5 bar, RT, 24h 2: 62 percent / H2, ammonium formate / 10percent Pd-C / methanol / Heating View Scheme
参考文献
Bringmann, Gerhard; Geisler, Joerg-Peter; Geuder, Torsten; Kuenkel, Georg; Kinzinger Lioba
Liebigs Annalen der Chemie, 1990 , # 8 p. 795 - 805
反应条件
[2,2']bipyridinyl; copper(l) iodide; oxygen in dimethyl sulfoxide T=140°C; 12 h; SolventTemperatureConcentrationReagent/catalyst;
参考文献
Huang, Pang-Chi; Gandeepan, Parthasarathy; Cheng, Chien-Hong
Chemical Communications, 2013 , vol. 49, # 76 p. 8540 - 8542
反应条件
1: hydroxylamine hydrochloride; sodium hydroxide / water; ethanol / |Reflux 2: iodine; triphenylphosphine; 1H-imidazole / dichloromethane / 4 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Paul, Saurav; Panda, Subhankar; Manna, Debasis
Tetrahedron Letters, 2014 , vol. 55, # 15 p. 2480 - 2483
反应条件
potassium carbonate in acetone
参考文献
Bringmann, Gerhard; Geisler, Joerg-Peter; Geuder, Torsten; Kuenkel, Georg; Kinzinger Lioba
Liebigs Annalen der Chemie, 1990 , # 8 p. 795 - 805
反应条件
oxygen; Co(Salpr) in methanol
24 h;
参考文献
Inada, Akira; Morita, Yutaka
Heterocycles, 1982 , vol. 19, # 11 p. 2139 - 2142
反应条件
in diethyl ether
T=-20 - 20°C;
参考文献
Gonzalez-Nogal, Ana M.; Calle, Mariola; Calvo, Luis A.; Cuadrado, Purificacion; Gonzalez-Ortega, Alfonso
European Journal of Organic Chemistry, 2005 , # 21 p. 4663 - 4669
反应条件
hydrogenchloride; water in methanol
T=50°C; 12 h;
参考文献
Huang, Jinbo; Mao, Tingting; Zhu, Qiang
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2878 - 2882
反应条件
potassium carbonate in tetrahydrofuran
28 h; Heating;
参考文献
Gao, Feng; Johnson, Kurtis F.; Schlenoff, Joseph B.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1996 , # 2 p. 269 - 274
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 20 °C / |Inert atmosphere
2: potassium carbonate / methanol / 2.5 h / 20 °C
3: hydrogenchloride; water / methanol / 12 h / 50 °C
View Scheme
参考文献
Huang, Jinbo; Mao, Tingting; Zhu, Qiang
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2878 - 2882
反应条件
1: potassium carbonate / methanol / 2.5 h / 20 °C
2: hydrogenchloride; water / methanol / 12 h / 50 °C
View Scheme
参考文献
Huang, Jinbo; Mao, Tingting; Zhu, Qiang
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2878 - 2882
