反应条件
1: N-(5-chloropyridin-2-yl)-2,2-dimethylpropionamide With n-butyllithium in tetrahydrofuran; hexane T=0°C; 2.5 h; 2: boric acid trimethyl ester in tetrahydrofuran; hexane T=-78 - 20°C; 3: With hydrogenchloride; water
参考文献
Basak, Arindrajit; Jin, Jeff; Moore, Jimmie; Pennell, Andrew M.K.; Punna, Sreenlvas; Ungashe, Solomon; Wei, Zheng
Patent: US2010/234364 A1, 2010 ;
Location in patent: Page/Page column 134 ;