(4-甲氧基苯氧基)乙酸乙酯合成路线 （共 15 条）
反应条件
hydrazine hydrate in ethanol Reflux;
参考文献
Maingot, Lucie; Elbakali, Jamal; Dumont, Julie; Bosc, Damien; Cousaert, Nicolas; Urban, Agathe; Deglane, Gaelle; Villoutreix, Bruno; Nagase, Hideaki; Sperandio, Olivier; Leroux, Florence; Deprez, Benoit; Deprez-Poulain, Rebecca
European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 244 - 261
反应条件
lithium aluminium tetrahydride in diethyl ether 1 h; Heating;
参考文献
Sankaraman,S.; Haney,W.A.; Kochi,J.K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 5235
参考文献
Thuillie,G.
Chimica Therapeutica, 1966 , vol. 1, p. 82 - 86
反应条件
1: hydrazine hydrate / methanol / 1 h / 20 °C 2: ethanol / 4 h / Reflux 3: phosphoric acid / 2 h / 120 °C View Scheme
参考文献
Sathisha; Khanum, Shaukath A.; Chandra, J.N. Narendra Sharath; Ayisha; Balaji; Marathe, Gopal K.; Gopal, Shubha; Rangappa
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 1 p. 211 - 220
反应条件
ethanethiol; AlCl3, aluminium chloride in dichloromethane
T=0°C; 0.666667 h;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1559422 A1, 2005 ;
Location in patent: Page/Page column 75 ;
EP 1559422 A1
