2,2,2-三氟-1-[(2S)-2-(羟基甲基)-1-吡咯烷基]乙酮合成路线 (共 3 条)
反应条件
triethylamine in methanol T=20°C; 18 h;
参考文献
Clark; Hodgson; Goldsmith; Blake; Cooke; Street
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 24 p. 3325 - 3337
反应条件
triethylamine; trifluoroacetic anhydride in dichloromethane; ethyl acetate
参考文献
Merck and Co., Inc.
Patent: US5756528 A1, 1998 ;
US 5756528 A
反应条件
sodium sulfate in tetrahydrofuran; water
参考文献
BONAC CORPORATION
Patent: US2012/10271 A1, 2012 ;