4-溴-1H-吲唑合成路线

参考文献

F. HOFFMANN-LA ROCHE AG; ALIAGAS-MARTIN, Ignacio; CRAWFORD, James; LEE, Wendy; MATHIEU, Simon; RUDOLPH, Joachim
Patent: WO2013/26914 A1, 2013 ;
Location in patent: Page/Page column 111 ;
WO 2013/026914 A1

557-21-1氰化锌+

186407-74-94-溴-1H-吲唑

861340-10-54-氰基-1H-吲唑

参考文献

F.HOFFMANN-LA ROCHE AG
Patent: WO2005/118539 A1, 2005 ;
Location in patent: Page/Page column 102-103 ;
WO 2005/118539 A1

186407-74-94-溴-1H-吲唑

861340-10-54-氰基-1H-吲唑

参考文献

Lohou, Elodie; Sopkova-De Oliveira Santos, Jana; Schumann-Bard, Pascale; Boulouard, Michel; Stiebing, Silvia; Rault, Sylvain; Collot, Valerie
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 17 p. 5296 - 5304

73183-34-3联硼酸频那醇酯+

186407-74-94-溴-1H-吲唑

885618-33-71H-吲唑-4-硼酸频哪醇酯

参考文献

Curis, Inc.; Bao, Rudi; Lai, Chengjung; Qian, Changgeng
Patent: US2013/102595 A1, 2013 ;
Location in patent: Paragraph 0173 ;

73183-34-3联硼酸频那醇酯+

186407-74-94-溴-1H-吲唑

271-44-3吲唑+

885618-33-71H-吲唑-4-硼酸频哪醇酯

参考文献

WO2007/127183 A1, ;

Page/Page column 138 ;
WO 2007/127183 A1

186407-74-94-溴-1H-吲唑

885521-72-24-溴-3-碘-1H-吲唑

参考文献

CONNEXIOS LIFE SCIENCES PVT. LTD.; RAO, Jagannath Madanahalli Ranganath; VENKATESHAM, Uppala; DOPPALAPUDI, Sivanageswara Rao; KENCHEGOWDA, Bommegowda Yadaganahalli; FERNAND, George; GEORGE, Jenson; MADHAVAN, G R; NAIDU, Gorle Paidapu; KADAMBARI, V. S. Naga Rajesh; JAGANNATH, S; MANIVANNAN, R; KUMAR, T Senthil; KUMAR, B Siva Senthil; MALLIKARJUNA, Rayi
Patent: WO2013/111150 A1, 2013 ;
Location in patent: Page/Page column 208; 209 ;

885675-66-12-氯-6-(4-甲烷磺酰基-哌嗪-1-甲基)-4-吗啉-4-基-噻吩并[3,2-D]嘧啶+

73183-34-3联硼酸频那醇酯+

186407-74-94-溴-1H-吲唑

957054-30-74-羟基-2,6-二甲基苯甲腈

参考文献

Journal of Medicinal Chemistry, , vol. 51, # 18 p. 5522 - 5532

186407-74-94-溴-1H-吲唑

957054-30-74-羟基-2,6-二甲基苯甲腈

参考文献

WO2011/130628 A1, ;
WO 2011/130628 A1

186407-74-94-溴-1H-吲唑

74626-47-4吲唑-5-甲腈

参考文献

Lohou, Elodie; Sopkova-De Oliveira Santos, Jana; Schumann-Bard, Pascale; Boulouard, Michel; Stiebing, Silvia; Rault, Sylvain; Collot, Valerie
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 17 p. 5296 - 5304

420-37-1三甲基氧鎓四氟硼酸+

186407-74-94-溴-1H-吲唑

590417-93-94-溴-2-甲基-2H-吲唑

参考文献

Takeda Pharmaceutical Company Limited
Patent: EP2141150 A1, 2010 ;
Location in patent: Page/Page column 63-64 ;