2-(4-溴苯基)-1,1-二苯基乙烯合成路线 （共 9 条）
反应条件
15-crown-5; sodium hydride in tetrahydrofuran T=20°C; Condensation; 24 h;
参考文献
Wang, Shujun; Oldham Jr., Warren J.; Hudack Jr., Raymond A.; Bazan, Guillermo C.
Journal of the American Chemical Society, 2000 , vol. 122, # 24 p. 5695 - 5709
反应条件
C17H15ClN7Pd(1+)*F6P(1-); potassium carbonate in water T=100°C; Suzuki-Miyaura cross-coupling reaction; 12 h;
参考文献
Gu, Shaojin; Xu, Hui; Zhang, Na; Chen, Wanzhi
Chemistry - An Asian Journal, 2010 , vol. 5, # 7 p. 1677 - 1686
反应条件
n-butyllithium in tetrahydrofuran; hexane T=-20°C; Wittig Reaction; 0.25 h;
参考文献
Kyocera Mita Corporation
Patent: JP2005/298421 A, 2005 ;
Location in patent: Page/Page column 27-28 ;
参考文献
Tetrahedron Letters, , vol. 52, # 12 p. 1329 - 1333
参考文献
Journal of the Chemical Society, , p. 439
反应条件
n-butyllithium in tetrahydrofuran T=-78 - 20°C; Inert atmosphere;
参考文献
Liang, Zuo-Qin; Li, Ye-Xin; Yang, Jia-Xiang; Ren, Yan; Tao, Xu-Tang
Tetrahedron Letters, 2011 , vol. 52, # 12 p. 1329 - 1333
反应条件
1: 1-(2-(4-bromophenyl)-1-phenylvinyl)benzene With n-butyllithium in tetrahydrofuran T=-78°C; 1 h; 2: tri-isopropoxy-borane in tetrahydrofuran T=-78 - 0°C; 1.5 h; 3: With hydrogenchloride; water
参考文献
DONGJIN SEMICHEM CO., LTD.
Patent: WO2009/51390 A2, 2009 ;
Location in patent: Page/Page column 70-72 ;
反应条件
1.1: n-BuLi / diethyl ether; tetrahydrofuran / 0.67 h / 0 - 20 °C 1.2: diethyl ether; tetrahydrofuran / 1.5 h / 20 °C 2.1: aq. H2SO4 View Scheme
参考文献
Jana, Debabrata; Ghorai, Binay K.
Tetrahedron Letters, 2012 , vol. 53, # 50 p. 6838 - 6842
反应条件
tri-tert-butyl phosphine; potassium tert-butylate; palladium diacetate in toluene
T=80°C; Buchwald-Hartwig coupling;
参考文献
Funabiki, Kazumasa; Mase, Hiroyoshi; Saito, Yasuteru; Otsuka, Atsuhiro; Hibino, Atsuhiko; Tanaka, Nagisa; Miura, Hidetoshi; Himori, Yosuke; Yoshida, Tsukasa; Kubota, Yasuhiro; Matsui, Masaki
Organic Letters, 2012 , vol. 14, # 5 p. 1246 - 1249
