N-Boc-2-氨基苯酚合成路线 （共 12 条）
反应条件
1: 88 percent / CH2Cl2; triethylamine / 16 h 2: 30 percent / t-BuLi; 1,2-diiodoethane / diethyl ether; pentane / 16 h / -80 - 20 °C 3: TFA 4: TBAF View Scheme
参考文献
Dumez, Estelle; Snaith, John S.; Jackson, Richard F. W.; McElroy, Andrew B.; Overington, John; Wythes, Martin J.; Withka, Jane M.; McLellan, Thomas J.
Journal of Organic Chemistry, 2002 , vol. 67, # 14 p. 4882 - 4892
反应条件
Montmorillonite K10 in dichloromethane deacylation; 2.25 h; Heating;
参考文献
Shaikh, Nadim S.; Gajare, Anil S.; Deshpande, Vishnu H.; Bedekar, Ashutosh V.
Tetrahedron Letters, 2000 , vol. 41, # 3 p. 385 - 387
反应条件
1: 77 percent / K2CO3 / acetone / 12 h / 20 °C 2: trifluoroacetic aciod / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Dubash, Nauzer P.; Mangu, Naveen K.; Satyam, Apparao
Synthetic Communications, 2004 , vol. 34, # 10 p. 1791 - 1799
反应条件
Cu(BF4)2
T=30 - 33°C; 1 h;
参考文献
Chankeshwara, Sunay V.; Chakraborti, Asit K.
Tetrahedron Letters, 2006 , vol. 47, # 7 p. 1087 - 1091
反应条件
potassium hydroxide in N,N-dimethyl-formamide
T=80°C; 2 h;
参考文献
Porzelle, Achim; Woodrow, Michael D.; Tomkinson, Nicholas C. O.
European Journal of Organic Chemistry, 2008 , # 30 p. 5135 - 5143
反应条件
potassium hydroxide in N,N-dimethyl-formamide
T=80°C; 2 h;
参考文献
Porzelle, Achim; Woodrow, Michael D.; Tomkinson, Nicholas C. O.
European Journal of Organic Chemistry, 2008 , # 30 p. 5135 - 5143
反应条件
tin; ammonium chloride in methanol
T=25°C; 4 h; Sonication;
参考文献
Chandrasekhar; Narsihmulu; Jagadeshwar
Synlett, 2002 , # 5 p. 771 - 772
反应条件
zinc(II) chloride in water; acetonitrile
T=20°C; 0.333333 h; chemoselective reaction;
参考文献
Arifuddin, M.; Lakshmikant, N.; Rajasekar, N.; Shinde, D. B.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 2012 , vol. 51, # 8 p. 1168 - 1172,5
反应条件
potassium phosphate in methanol
0.166667 h; Reflux;
参考文献
Dandepally, Srinivasa Reddy; Williams, Alfred L.
Tetrahedron Letters, 2009 , vol. 50, # 9 p. 1071 - 1074
反应条件
Streptomyces lividans expressing pIJ6021-bphA1(2072)A2A3A4
T=30°C; 24 h; Microbiological reaction;
参考文献
Shindo, Kazutoshi; Nakamura, Ryoko; Chinda, Ikuko; Ohnishi, Yasuo; Horinouchi, Sueharu; Takahashi, Haruko; Iguchi, Kazuo; Harayama, Shigeaki; Furukawa, Kensuke; Misawa, Norihiko
Tetrahedron, 2003 , vol. 59, # 11 p. 1895 - 1900
