3-氨基-7-氯-1,2,4-苯并三嗪-1-氧化物合成路线 （共 3 条）
反应条件
ethanol; nickel Hydrogenation;
参考文献
Wolf et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 3551
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Merck and Co. Inc.
Patent: US2489351 , 1946 ;
反应条件
1: hydrogenchloride; trifluoroacetic acid; sodium nitrite / water / 1 h / 20 °C 2: trichlorophosphate / 3 h / Reflux View Scheme
参考文献
Chopra, Sidharth; Koolpe, Gary A.; Tambo-Ong, Arlyn A.; Matsuyama, Karen N.; Ryan, Kenneth J.; Tran, Tran B.; Doppalapudi, Rupa S.; Riccio, Edward S.; Iyer, Lalitha V.; Green, Carol E.; Wan, Baojie; Franzblau, Scott G.; Madrid, Peter B.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 13 p. 6047 - 6060
反应条件
acetic acid T=50°C; 4 h;
参考文献
Hay, Michael P.; Gamage, Swarna A.; Kovacs, Mary S.; Pruijn, Frederik B.; Anderson, Robert F.; Patterson, Adam V.; Wilson, William R.; Brown, J. Martin; Denny, William A.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 169 - 182
