hydrogenchloride; pentabromo-phenol; trimethylaluminum in dichloromethane T=-78 - 20°C; 336000 h; Acid hydrolysis;

1: 98 percent / K2CO3 / acetone / 12 h 2: 56 percent / pentabromophenol; HCl / trimethylaluminum / CH2Cl2 / 336000 h / -78 - 20 °C / Acid hydrolysis View Scheme

1.1: NaH / tetrahydrofuran / 4 h / 0 - 20 °C 1.2: 70 percent / HCl / tetrahydrofuran / 8 h / Acid hydrolysis 2.1: 98 percent / K2CO3 / acetone / 12 h 3.1: 56 percent / pentabromophenol; HCl / trimethylaluminum / CH2Cl2 / 336000 h / -78 - 20 °C / Acid hydrolysis View Scheme

T=190°C;