6-氨基-2,2-二甲基-苯并二氢吡喃-4-酮合成路线 （共 5 条）
反应条件
hydrogenchloride in ethanol 3 h; Reflux;
参考文献
Florence, Xavier; Dilly, Sebastien; De Tullio, Pascal; Pirotte, Bernard; Lebrun, Philippe
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 13 p. 3919 - 3928
反应条件
1: pyrrolidine / methanol / 25 °C 2: hydrogenchloride / ethanol / 3 h / Reflux View Scheme
参考文献
UNIVERSITE DE LIEGE; UNIVERSITE LIBRE DE BRUXELLES; GOFFIN, Eric; DE TULLIO, Pascal; FLORENCE, Xavier; PIROTTE, Bernard; ROGISTER, Bernard; LAMORAL-THEYS, Delphine; LEFRANC, Florence; KISS, Robert
Patent: WO2012/107262 A1, 2012 ;
反应条件
1: AlCl3, aluminium chloride / carbon disulfide / 1.5 h 2: pyrrolidine / methanol / 25 °C 3: hydrogenchloride / ethanol / 3 h / Reflux View Scheme
参考文献
UNIVERSITE DE LIEGE; UNIVERSITE LIBRE DE BRUXELLES; GOFFIN, Eric; DE TULLIO, Pascal; FLORENCE, Xavier; PIROTTE, Bernard; ROGISTER, Bernard; LAMORAL-THEYS, Delphine; LEFRANC, Florence; KISS, Robert
Patent: WO2012/107262 A1, 2012 ;
反应条件
1: sodium acetate; acetic acid 2: AlCl3, aluminium chloride / carbon disulfide / 1.5 h 3: pyrrolidine / methanol / 25 °C 4: hydrogenchloride / ethanol / 3 h / Reflux View Scheme
参考文献
UNIVERSITE DE LIEGE; UNIVERSITE LIBRE DE BRUXELLES; GOFFIN, Eric; DE TULLIO, Pascal; FLORENCE, Xavier; PIROTTE, Bernard; ROGISTER, Bernard; LAMORAL-THEYS, Delphine; LEFRANC, Florence; KISS, Robert
Patent: WO2012/107262 A1, 2012 ;
反应条件
1: sodium hydroxide; water 2: pyrrolidine; acetone / 20 °C 3: hydrogenchloride / ethanol / 3 h / Reflux View Scheme
参考文献
Université de Liège; Université Libre de Bruxelles
Patent: EP2487171 A1, 2012 ;
