6-(甲基磺酰基)-3-吡啶胺合成路线 (共 4 条)
反应条件
iron; ammonium chloride in methanol; water 1 h; Reflux;
参考文献
ELI LILLY AND COMPANY; BLEISCH, Thomas, John; COATES, David, Andrew; HUGHES, Norman, Earle; JONES, Scott, Alan; NORMAN, Bryan, Hurst
Patent: WO2013/66640 A1, 2013 ;
Location in patent: Page/Page column 19 ;
反应条件
acetic acid in water; ethyl acetate
参考文献
Pfizer Inc.
Patent: US6531492 B1, 2003 ;
反应条件
1: sulfuric acid; potassium permanganate / water; acetone / 20 °C 2: ammonium chloride; iron / water; methanol / 1 h / |Reflux View Scheme
反应条件
1: triethylamine / methanol / 2 h / 20 °C 2: sulfuric acid; potassium permanganate / water; acetone / 20 °C 3: ammonium chloride; iron / water; methanol / 1 h / |Reflux View Scheme