双环[2.2.1]庚烷-1-羧酸合成路线 （共 28 条）
反应条件
1: 73 percent / 85percent H2O2 2: 4 percent Chromat. / benzene / 81 °C View Scheme
参考文献
Fossey, Jacques; Lefort, Daniel
Tetrahedron, 1980 , vol. 36, # 81 p. 1023 - 1036
反应条件
1: LiAlH4 2: 85 percent / 30percent fuming H2CO4, conc. H2SO4 / 2.5 h / 0 °C 3: 4.74 g / conc. HCl / 48 h / Heating View Scheme
参考文献
Chae, Woo-Ki; Baughman, Sharon A.; Engel, Paul S.; Bruch, Manfred; Oezmeral, Cenan; et al.
Journal of the American Chemical Society, 1981 , vol. 103, # 16 p. 4824 - 4833
反应条件
1: SOCl2
2: aq. NH3
View Scheme
参考文献
Greene,F.D. et al.
Journal of Organic Chemistry, 1963 , vol. 28, p. 55 - 64
参考文献
Applequist,D.E.; Kaplan,L.
Journal of the American Chemical Society, 1965 , vol. 87, p. 2194 - 2200
反应条件
1: 0.56 g / LiAlH4
2: 80 percent / pyridine / CH2Cl2 / 96 h
3: 83 percent / LiBr / tetrahydrofuran / 48 h / Heating
View Scheme
参考文献
Della, Ernest W.; Knill, Andrew M.; Pigou, Paul E.
Journal of Organic Chemistry, 1993 , vol. 58, # 8 p. 2110 - 2114
反应条件
1: SOCl2
2: (i) Py, (ii) H2O
View Scheme
参考文献
Greene,F.D. et al.
Journal of Organic Chemistry, 1963 , vol. 28, p. 55 - 64
反应条件
sulfuric acid; dihydrogen peroxide
8 h; Ambient temperature;
参考文献
Della,G.W.; Cotsaris,E.; Hine,P.T.
Journal of the American Chemical Society, 1981 , vol. 103, p. 4131
反应条件
1: LiAlH4
2: 85 percent / 30percent fuming H2CO4, conc. H2SO4 / 2.5 h / 0 °C
View Scheme
参考文献
Chae, Woo-Ki; Baughman, Sharon A.; Engel, Paul S.; Bruch, Manfred; Oezmeral, Cenan; et al.
Journal of the American Chemical Society, 1981 , vol. 103, # 16 p. 4824 - 4833
