1-(4-三氟甲氧基苯基)哌嗪合成路线 (共 2 条)
反应条件
sodium t-butanolate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene
T=20°C; 1 h; Heating / reflux;
参考文献
Applied Research Systems ARS Holding N.V.
Patent: WO2006/10751 A1, 2006 ;
Location in patent: Page/Page column 84-85 ;
反应条件
T=20 - 165°C; neat (no solvent);
参考文献
Konstantinova, Igor; Bukhryakov, Konstantin; Gezentsvey, Yuri; Krasavin, Mikhail
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 628 - 630