2-氨基-5-(4-硝基苯基)-1H-吡咯-3-羧酸乙酯合成路线 （共 2 条）
反应条件
1: ethyl 2-amidinoacetate hydrochloride With sodium ethanolate in ethanol T=0 - 5°C; 0.333333 h; 2: 2-bromo-4'-nitroacetophenone in ethanol T=20°C; 24 h;
参考文献
CURIS, INC.
Patent: WO2008/33745 A2, 2008 ;
Location in patent: Page/Page column 79-80 ;
WO 2008/033745 A2
反应条件
1: ethyl 2-amidinoacetate hydrochloride With sodium ethanolate in ethanol T=0 - 5°C; 0.333333 h; 2: 2-bromo-4'-nitroacetophenone in ethanol T=20°C; 24 h;
参考文献
CURIS, INC.
Patent: WO2008/33747 A2, 2008 ;
Location in patent: Page/Page column 264 ;
