4alpha-苄基-2,3,4,4alpha-四氢-1H-咔唑合成路线 （共 10 条）
反应条件
Beim 24-stdg. Erhitzen;
参考文献
Nakasaki et al.
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1262,1264
Chem.Abstr., 1957 , p. 17878
反应条件
(η3-allyl)2Pd(cod)BF4; triethyl borane; potassium phenolate; bis[2-(diphenylphosphino)phenyl] ether in toluene
T=75°C; 16 h; Inert atmosphere;
参考文献
Montgomery, Thomas D.; Zhu, Ye; Kagawa, Natsuko; Rawal, Viresh H.
Organic Letters, 2013 , vol. 15, # 5 p. 1140 - 1143
反应条件
1: 1,2,3,4-tetrahydrocarbazole With potassium tert-butylate in 1,4-dioxane
T=20°C; 0.5 h; Inert atmosphere;
2: With triethyl borane in 1,4-dioxane; hexane
0.5 h; Inert atmosphere;
3: benzyl bromide in 1,4-dioxane; hexane
T=20°C; 12 h; Inert atmosphere;
参考文献
Lin, Aijun; Yang, Jiong; Hashim, Mohamed
Organic Letters, 2013 , vol. 15, # 8 p. 1950 - 1953
反应条件
1: 1,2,3,4,10,11-hexahydrocarbazole With (η3-allyl)2Pd(cod)BF4; bis[2-(diphenylphosphino)phenyl] ether in toluene
T=20°C; 0.0833333 h; Inert atmosphere;
2: PhCH2OCO2Me With N,O-bis-(trimethylsilyl)-acetamide; triethyl borane in hexane; toluene
T=50°C; 18 h; Inert atmosphere;
参考文献
Zhu, Ye; Rawal, Viresh H.
Journal of the American Chemical Society, 2012 , vol. 134, # 1 p. 111 - 114
反应条件
1.1: sodium hydride / mineral oil; tetrahydrofuran / 0.5 h / 0 °C / |Inert atmosphere
1.2: 20 °C / |Inert atmosphere
2.1: (η3-allyl)2Pd(cod)BF4; potassium phenolate; triethyl borane; bis[2-(diphenylphosphino)phenyl] ether / toluene / 16 h / 75 °C / |Inert atmosphere
View Scheme
参考文献
Montgomery, Thomas D.; Zhu, Ye; Kagawa, Natsuko; Rawal, Viresh H.
Organic Letters, 2013 , vol. 15, # 5 p. 1140 - 1143
反应条件
hydrogenchloride
T=180°C;
参考文献
Nakasaki et al.
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1262,1264
Chem.Abstr., 1957 , p. 17878
反应条件
acetic acid
T=170°C;
参考文献
Nakazaki; Isoe
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1159,1167
Chem.Abstr., 1957 , p. 17877
反应条件
ammonia; sodium; iron nitrate (III)
anschl. mit Benzylchlorid;
参考文献
Nakazaki; Isoe
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1159,1167
Chem.Abstr., 1957 , p. 17877
参考文献
Nakazaki; Isoe
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1159,1167
Chem.Abstr., 1957 , p. 17877
参考文献
Nakasaki et al.
Nippon Kagaku Zasshi, 1955 , vol. 76, p. 1262,1264
Chem.Abstr., 1957 , p. 17878
