反应条件
1.1: 85 percent / aq. H2O2 / CH2Cl2; H2O / 1 h
2.1: DIBAL-H / CH2Cl2; toluene / 1 h / -78 °C
3.1: 151 mg / pyridinium p-toluenesulfonate / benzene / 2 h / 25 °C
4.1: 91 percent / Bu4NF / tetrahydrofuran / 1 h
5.1: 90 percent / TPAP; N-methylmorpholine N-oxide; molecular sieves 4 Angstroem / CH2Cl2 / 0.5 h / 25 °C
6.1: 75 percent / t-BuOK / toluene; tetrahydrofuran / 2 h / 0 °C
7.1: CeCl3; t-BuLi / tetrahydrofuran; diethyl ether / 0.17 h / -78 °C
7.2: tetrahydrofuran; diethyl ether; toluene / 0.08 h / -78 °C
8.1: PPTS / 2 h / 25 °C
9.1: Et3N / DMAP / CH2Cl2 / 1 h
10.1: 2,6-lutidine / CH2Cl2 / 0.75 h / -20 °C
11.1: aq. HCl / acetone / 2 h / -15 - 0 °C
12.1: 40 percent / Ag2CO3-Celite / benzene / 2 h / 80 °C
13.1: PCl3; pyridine / 0.25 h / 25 °C
13.2: 1 h
14.1: 3.9 mg / aq. H2O2 / CH2Cl2; pyridine / 0.5 h
15.1: aq. HF / acetonitrile / 0.25 h / 25 °C
15.2: aq. HF; pyridine / acetonitrile / 168000 h
View Scheme
参考文献
Boger; Ichikawa; Zhong
Journal of the American Chemical Society, 2001 , vol. 123, # 18 p. 4161 - 4167
