5-氨基-1-(4-氟苯基)-1H-吡唑-4-羧酸合成路线 （共 2 条）
反应条件
1: With lithium hydroxide; water in methanol 17 h; Heating / reflux; 2: With hydrogenchloride in water pH=7;
参考文献
CHROMA THERAPEUTICS LTD.
Patent: WO2008/53136 A1, 2008 ;
Location in patent: Page/Page column 36 ;
WO 2008/053136 A1
反应条件
1: ethanol / 16 h / Heating 2: aq. LiOH / methanol / 16 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 49, # 5 p. 1562 - 1575
