(S)-4-(4-肼基苄基)-2-恶唑烷酮合成路线 (共 3 条)
反应条件
1: With hydrogenchloride in water T=90°C; 1 h; 2: With sodium hydroxide in water pH=7;
参考文献
Mittapelli, Vasantha; Ray, Puma Chandra; Chauhan, Yogendra Kumar; Datta, Debashish
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2009 , vol. 48, # 4 p. 590 - 594
反应条件
1: With hydrogenchloride in water T=25 - 90°C; pH=2 - 9; 5 - 6 h; 2: With sodium carbonate in water pH=~ 8 - 9;
参考文献
GENERICS [UK] LIMITED
Patent: US2011/112157 A1, 2011 ;
Location in patent: Page/Page column 11 ;
反应条件
T=90 - 98°C; 2.5 h; Heating / reflux; Product distribution / selectivity;
参考文献
ZENTIVA, A.S.
Patent: WO2008/104135 A1, 2008 ;
Location in patent: Page/Page column 4 ;