1: CF3COOH / 0.25 h / Ambient temperature 2: acetonitrile / 15 h / Ambient temperature 3: CF3COOH / 0.33 h / Ambient temperature 4: acetonitrile / 15 h / Ambient temperature 5: 85.4 percent / H2, AcOH / Pd black / methanol / 3 h / Ambient temperature View Scheme

hydrogen; palladium on activated charcoal in acetic acid

1: acetic acid / 5 percent Pd/C / 72 h 2: 50 percent TFA / CH2Cl2 3: 20 percent aq. NaHCO3 / CH2Cl2 / 72 h / 20 °C View Scheme

1: acetic acid / 5 percent Pd/C / 72 h 2: 50 percent TFA / CH2Cl2 View Scheme

1: CF3COOH / 0.25 h / Ambient temperature 2: acetonitrile / 15 h / Ambient temperature View Scheme

1: CF3COOH / 0.25 h / Ambient temperature 2: acetonitrile / 15 h / Ambient temperature 3: CF3COOH / 0.33 h / Ambient temperature 4: acetonitrile / 15 h / Ambient temperature 5: 1.) H2, AcOH, 2.) H+ / 1.) Pd black / 1.) RT, 5 d View Scheme